The promotion will run for seven days, until midnight next Monday, November 26, which is two days longer than last year.
TUI says there will be deals available across TUI holidays, First Choice all-inclusive breaks and Marella Cruises.
The company has launched a guide for customers telling them how to make the most of the promotion.
TUI has confirmed that, like last year, customers who book a Black Friday deal will automatically be entered into a free competition to win back the cost of their trip.
Entry is automatic for all customers who book a Black Friday deal online or in store.
TUI says it expects a similar range of discounts this year to last, with different holidays available at reduced prices on different days before and after Black Friday. The company says it recommends keeping up to date with TUI so you can book the holiday of your dreams for a bargain price.