Saga Cruises and AmaWaterways have become the latest cruise companies to announce they are suspending operations, following a warning from the Government against over-70s and those with serious medical conditions to avoid cruises.
Saga has suspended its cruise operations until May 1 and has warned its profits will be hit.
Customers who were due to travel in the next six weeks will be offered either a full refund or credit for a future departure.
It said suspending its cruise operations for the next six weeks would reduce profit in the division by between £10m and £15m.
AmaWaterways has delayed the start of its European sailing season to April 26 and is suspending Mekong River cruises, due to start on March 23.
Guests who were booked on a cruise that is being cancelled have the option of receiving a Future Cruise Credit equal to 115% of the value of all services purchased through AmaWaterways or receiving a full monetary refund.
The Future Cruise Credit is applicable on all European or Mekong River cruise sailings any time before December 31, 2022.